Does NMN Increase Testosterone?
During the use of NMN to boost energy levels and cognitive function, many men have noticed a significant increase in their testosterone levels. Indeed, NMN indirectly affects the rise of testosterone levels in the serum, leading to a strong improvement in male reproductive health.
Before exploring further, please read the disclaimer located at the end of this webpage.
Key Takeaways
- NMN helps increase testosterone levels through an indirect mechanism that affects NAD+ levels, thereby improving the function of Leydig cells responsible for testosterone production.
- Many animal studies have shown that NMN helps increase testosterone levels in the serum.
- Consider a dosage of 250–500 mg of NMN per day, used continuously for 6-12 weeks, to achieve noticeable results.
- The wormwood tincture mixture can be stored for up to 1-2 years.
Does NMN Increase Testosterone?
The answer is yes, NMN does increase testosterone. However, many scientific studies indicate that NMN does not directly increase the amount of testosterone in the serum; rather, it relies on indirect mechanisms during cellular energy metabolism to help boost testosterone levels.
How Does NMN Increase Testosterone?
Specifically, most studies indicate that NMN has an indirect effect in supporting the maintenance and improvement of testosterone levels through the mechanism of enhancing NAD+. NAD+, in turn, has the ability to improve the function of Leydig cells, which are responsible for producing testosterone in the testes.
Thus, when NAD+ levels increase due to the effects of NMN, it helps Leydig cells function more effectively. As a result, testosterone levels may be maintained or significantly improved.
What Science Say About NMN and Testosterone
Many animal studies have shown that NMN can improve testosterone levels, as detailed below:
Study 1 [1]:
This study was conducted on 32 male Landrace pigs, randomly divided into NMN and non-NMN groups. Over 9 weeks and 2 days, the NMN groups were supplemented with 8, 16, and 32 mg NMN/kg/day (dosage varied based on the pigs' weight).
Results: The NMN group showed a significant increase in serum NAD+ and NADH levels, and the NAD+/NADH ratio was also higher (p<0.05). Thus, NMN supplementation through the diet helped increase NAD+ levels, which indirectly led to a significant increase in testosterone levels in male pigs.
Study 2 [2]:
The study focused on ANDY genetically modified mice, in which NAD+ levels were reduced, resulting in an inability to produce testosterone, smaller testicles, and reduced sperm count. NMN was supplemented to these mice, and changes were monitored.
Results: The NMN-supplemented mice showed positive signals, including improved testosterone levels and restored testicular health.
Other Benefits of NMN Supplements for Men
Anti-Aging: NMN is considered the number one ally against aging, as it helps maintain cellular functions and slows down the aging process in older adults [3].
Cell Improvement: NMN helps increase NAD+ levels, improving cellular functions and providing energy to cells [4].
Brain Function Support: NMN also helps protect nerve cells, enhance cognition and memory, improve mood, and prevent anxiety, depression, and memory decline [5].
Cardiovascular Health: NMN helps men boost testosterone levels, which in turn regulates cholesterol levels and maintains vascular functions.
Muscle Recovery and Strength: Reduced testosterone levels can lead to decreased muscle mass and strength, affecting physical fitness in men.
Therefore, supplementing with NMN is also essential for muscle development and recovery after intense exercise.
Reproductive Health: NMN indirectly increases sexual desire and improves sperm production in men.
How to Use NMN Supplement to Increase Testosterone
To use NMN correctly, you can follow these guidelines:
Dosage: NMN is considered safe when used at a dosage of 250-500 mg per day [6] [7].
Duration: For 6-12 weeks [6].
Be sure to consult with your doctor and monitor your body's reactions during the usage period to adjust the dosage as needed.
Frequently Asked Questions
Can You Combine NMN Supplement with Tongkat Ali for Testosterone?
The answer is yes, you can combine NMN with Tongkat Ali—a root known for its effects on enhancing male sexual health. Combining the two will help you maximize the reproductive health benefits of both.
Can NAD+ Increase Testosterone Levels?
Yes, NAD+ indirectly affects testosterone levels by improving the function of Leydig cells. If NAD+ levels are high, testosterone levels will change significantly.
Does NMN affect hormone levels?
NMN does affect hormone levels, but the specific impact on various types of hormones and the exact processes involved still require further research for clarification.
Conclusion
The overall benefits of NMN, such as increasing testosterone levels and improving reproductive health in men, are reasons why you should consider adding NMN to your daily diet. Why wait? Start using NMN in your 30s or 40s to enhance your health.
References
- [1] Supplementing Boar Diet with Nicotinamide Mononucleotide Improves Sperm Quality Probably through the Activation of the SIRT3 Signaling Pathway Antioxidants (Basel). 2024 May; 13(5): 507. Published online 2024 Apr 24. doi: 10.3390/antiox13050507
- [2] Low NAD+ Levels Are Associated With a Decline of Spermatogenesis in Transgenic ANDY and Aging Mice Front Endocrinol (Lausanne). 2022; 13: 896356. Published online 2022 May 6. doi: 10.3389/fendo.2022.896356
- [3] The Science Behind NMN–A Stable, Reliable NAD+Activator and Anti-Aging Molecule Integr Med (Encinitas). 2020 Feb; 19(1): 12–14. PMCID: PMC7238909PMID: 32549859
- [4] The role of nicotinamide mononucleotide (NMN) in anti-aging, longevity, and its potential for treating chronic conditions Review Published: 20 April 2022 Volume 49, pages 9737–9748, (2022)
- [5] NAD+ in Brain Aging and Neurodegenerative Disorders Cell Metab. Author manuscript; available in PMC 2020 Oct 1. Published in final edited form as Cell Metab. 2019 Oct 1; 30(4): 630–655. doi: 10.1016/j.cmet.2019.09.001
- [6] Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle motility in healthy old men https://doi.org/10.21203/rs.3.rs-455083/v1
- [7] Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese Men 2020 Volume 67 Issue 2 Pages 153-160 DOI https://doi.org/10.1507/endocrj.EJ19-0313
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