Is There Hydroxytyrosol In Olive Leaf Extract?

Hydroxytyrosol is no longer unfamiliar to those seeking a natural ingredient with exceptional antioxidant properties, commonly found in olive leaves.

So, what benefits and potential side effects does this compound offer? How should it be incorporated into daily routines in the most convenient and effective forms? Let’s dive deeper into today’s article to explore hydroxytyrosol and its potential.

Is There Hydroxytyrosol In Olive Leaf Extract?

The answer is yes; research has confirmed that phenolic extract from olive leaves contains a high level of hydroxytyrosol, a compound with strong antioxidant properties [1].

This compound is a fundamental component of olive leaves and contributes to the formation of other phenolic compounds, such as oleuropein and other glycosides.

Benefits Of Hydroxytyrosol In Olive Leaf

Antioxidant Properties

Hydroxytyrosol is one of the strongest antioxidant phenolic compounds found in olive leaves, acting through the following mechanisms [2]: eliminating free radicals (including superoxide and hypochlorous acid); protecting unsaturated fatty acids on the outer layer of LDL; inhibiting LDL oxidation caused by CuSO4; and reducing the formation of new free radicals from free metals.

Cardiovascular Health

Hydroxytyrosol, with its ability to inhibit LDL oxidation, supports preventing the formation of atherosclerotic plaques, thereby reducing the risk of cardiovascular diseases.

Additionally, this compound can stimulate the production of substances such as interleukin-6 and thromboxane, reduce platelet aggregation, and enhance protection against circulatory and heart-related conditions.

Neuroprotective Effects

Currently, there is not much in-depth research on this specific benefit of hydroxytyrosol. However, based on its exceptional antioxidant properties, hydroxytyrosol still indirectly provides benefits in protecting the nervous system from age-related degeneration.

Antimicrobial Activity

Hydroxytyrosol has been shown to possess antibacterial properties due to its unique structure, which can kill or inhibit the growth of various types of bacteria, as demonstrated in the following studies [2]:

• Study 1: The o-diphenol structure of hydroxytyrosol plays a significant role in its strong antibacterial effects, as it has high sensitivity and helps prevent the growth of many bacteria, such as Gram-positive bacteria.
• Study 2: High concentrations of hydroxytyrosol can inhibit various bacteria, including E. coli and Staphylococcus aureus. However, its effectiveness depends on certain culturing conditions, resulting in varying levels of efficacy.
• Study 3: An experimental study tested the effects of the compound on Mycoplasma hominis and Pneumoniae strains. The results showed that hydroxytyrosol was effective in inhibiting the growth of these bacteria at low concentrations.

Skin Health

Currently, some potential benefits of hydroxytyrosol for the skin include protecting the skin from external harmful factors and nourishing it for healthy growth; slowing down the aging process as you get older; maintaining skin elasticity; and supporting in preventing UV damage if you are exposed to sunlight due to work-related factors.

Other Potential Benefits

In addition to the benefits mentioned above, the compound also contributes to overall health protection for users over the long term through abilities such as reducing endothelial dysfunction, improving blood fluidity, and enhancing cell adhesion.

How Much Hydroxytyrosol In Olive Oil?

In a trial with 9 volunteers divided into two groups with different dosages, one group received a low dose of olive leaf extract (containing 9.7 mg of hydroxytyrosol), and the other received a higher dose (containing 14.5 mg of hydroxytyrosol).

The results showed that both dosages were safe for use. Therefore, you can consider using olive leaf extract with hydroxytyrosol content ranging from 9.7 mg to 14.5 mg [3].

For dosage customization, you may want to consult with a doctor to develop the safest and most effective usage plan. However, to ensure safety, you should use it in doses below 0.32mM/day, which corresponds to a dose lower than 172.97 mg/day, to avoid potential toxicity to your body and cells.

Incorporating Hydroxytyrosol Into Your Daily

To incorporate hydroxytyrosol into your daily routine, you can start with the following methods:

• Olive oil: If you're still using regular oils like soybean oil for cooking, it's time to switch to olive oil. Using olive oil will help your body consistently receive a suitable amount of hydroxytyrosol each day.
• Olive powder: If you want to combine it with other foods, rather than just using it for frying or sautéing, as mentioned above, you can use olive powder in juice, smoothies, or snacks. The hydroxytyrosol absorbed through this method will also bring significant benefits to your body.
• Supplements: Sometimes, adding hydroxytyrosol to food and drinks can be inconvenient and may affect its effectiveness. That's why I suggest considering supplements containing hydroxytyrosol. These products ensure you get the right amount of hydroxytyrosol while being convenient and safe for long-term use.

Which Olives Are Highest In Hydroxytyrosol?

Green olives (unripe) or those that have not been processed typically contain the highest levels of hydroxytyrosol. For ripe olives or those that have undergone processing, some of the hydroxytyrosol may be lost in the extraction process. However, processing is necessary to remove unwanted substances from the fruit and ensure a higher level of purity and safety.

Hydroxytyrosol Side Effects

According to research, hydroxytyrosol is safe when used at the recommended dosage. However, if used in high doses above 0.32mM, this compound may be toxic to NIH/3T3 cells and human vascular endothelial cells [1]. Additionally, it can cause some side effects, such as digestive disturbances and skin irritation, when used at high concentrations.

Dosage And Safety

Currently, studies on the dosage of hydroxytyrosol for human health are still being further evaluated. However, to ensure safety, it is recommended to use it at a dose lower than 0.32mM per day to avoid potential toxicity to the body and cells. For personalized dosage adjustments, it is advisable to consult a doctor to create the most optimal and safe usage plan.

Conclusion

Hydroxytyrosol extract from olive leaves is a safe option for those seeking solutions for antioxidant support, cardiovascular protection, nervous system health, antibacterial properties, and skin improvement. However, when using it, it is important to carefully consider the appropriate dosage based on individual needs and health conditions to avoid potential toxicity to the cells.