Does Milk Thistle Detox the Liver?

Currently, liver health is an issue that many people are concerned about. One of the popular ways to enhance liver health is to use natural herbs, the most prominent of which is milk thistle. Many people wonder if milk thistle helps detoxify the liver. This article will provide an overview of the effects of milk thistle on liver health and answer the question: Does Milk Thistle Detox the Liver?

What is Milk Thistle?

Milk thistle has the scientific name Silybum Marianum. It is named after the milky white veins of the leaves, just like the milk of the Virgin Marina. Therefore, it is also known as Mary Thistle or Holy Thistle.

This flowering plant originates from the Mediterranean region and is found in most countries: America, Africa, Asia, and today. They have been used over 2000 years as a natural remedy for liver-related diseases [1].

The main active ingredient contained in milk thistle is Sylimarin. The flavonoid complex is known for its antioxidant, anti-inflammatory, and hepatoprotective properties [2].

Does Milk Thistle Detox the Liver?

Milk thistle does not directly detoxify the liver. Because the liver has its detoxification mechanism, eliminating its own toxins.

Milk thistle's effect is to protect and enhance liver health through Silymarin indirectly. The active ingredient, Silymarin, has antioxidant properties, reduces inflammation, and helps protect liver cells from damage caused by free radicals.

Besides, the anti-inflammatory effect of Silymarin stimulates the growth of new liver cells, reducing the risk of hepatitis in humans [3].

Milk Thistle for Liver Detox: The Scientific Evidence

As mentioned above, Milk Thistle cannot detoxify the liver. Because the liver has its mechanism to eliminate toxins. Even so, Milk Thistle is said to support liver health in several ways:

Antioxidant Properties

Based on previously conducted research, the compound Silymarin has high antioxidant properties, keeping toxins in the blood from sticking to liver cells and indirectly contributing to liver detoxification.

In addition, Silymarin found in milk thistle also helps neutralize free radicals, which are unstable molecules that originate from byproducts of the body's metabolism and can be harmful to the body—healthy cells [4].

Anti-inflammatory Effect

Medical research on milk thistle and liver health shows that Silymarin has anti-inflammatory properties and promotes liver cell repair. By reducing inflammation, milk thistle creates a healthy environment for healthy liver cells to grow [5].

Protect Liver Cells

Based on research conducted in 2002 related to Silymarin and liver health, it was found that this active ingredient protects liver cells and enhances liver function [6].

Besides, it is also helpful in stimulating the growth of new liver cells and preventing lipid peroxidation. From there, it reduces liver enzyme levels in the blood, improving signs and symptoms of liver-related diseases.

Liver Cell Regeneration

Studies show that Silymarin can stimulate the growth of new liver cells, which is essential for repairing and restoring damaged liver tissue. This regenerative property can help improve liver function and overall health [6].

Studies have shown that Milk Thistle may be beneficial for supporting liver health. However, it should not be considered a stand-alone treatment for liver diseases. So, consult a healthcare professional before starting to supplement with Milk Thistle extracts.

How Does Milk Thistle Benefit for Specific Liver Conditions?

Cirrhosis

Cirrhosis is the final progression of liver damage. Although it cannot be used to support cirrhosis completely, milk thistle has the ability to slow the progression of cirrhosis by reducing inflammation and antioxidants in the liver.

Thanks to the antioxidant properties of Silymarin, it helps protect liver cells from the spread of harmful cells, reducing chronic inflammation related to cirrhosis. Silymarin also contributes to promoting liver cell regeneration, supporting the repair of damaged liver tissue [4].

Hepatitis

Hepatitis is often caused by a viral infection that causes significant loss of liver function. Although it is effective in treating diseases related to liver conditions such as cirrhosis, alcoholic and non-alcoholic fatty liver disease, liver cancer, etc., up to now, there has been no research to prove its effectiveness in Anti-hepatitis effects of milk thistle.

One study found that people with hepatitis did not benefit from changes in viral load or quality of life even when taking higher-than-normal doses of Silymarin [7].
Non-alcoholic fatty liver disease

According to research by Ludovico Abenavoli and colleagues, milk thistle protects liver cells from fatty infiltration by enhancing the liver's ability to process and eliminate excess fat [8].

In addition to this effect of milk thistle, Trappoliere M and colleagues have also shown positive results that milk thistle can improve insulin sensitivity and lipid metabolism, preventing the destruction of liver cells. , one of the causes of non-alcoholic fatty liver disease [9].

Alcoholic-related liver disease (ARLD)

Alcohol-related liver disease (ARLD) is caused by patients drinking too much alcohol, leading to damage to liver cells. As analyzed above, milk thistle is effective in stimulating the growth of new liver cells, contributing to the restoration of liver function in people with ARLD. However, improving this situation will take much time [6].

Liver cancer

Research into the effects of milk thistle, as well as Silymarin, on liver cancer, is still in its early stages. However, some small studies also suggest that Silymarin may have anti-cancer properties or protect the liver from cancer cells. In the future, further research may be conducted on Silymarin's ability to inhibit cancer cell growth.

What are Milk Thistle Liver Detox Symptoms?

Digestive Problems

Symptoms associated with the liver detoxifying activity of milk thistle are usually mild and may vary depending on the individual. One of these symptoms is digestive problems, including bloating or swelling in the abdomen, increased intestinal gas causing discomfort, belching, diarrhea, nausea, etc.

Allergic Reaction

Although rare, milk thistle cannot be ruled out as causing allergic reactions in humans. These symptoms can include rash, persistent itching on the skin, swelling of the face, lips, tongue, or throat, etc. This condition can be severe if not detected and improved promptly.

Headache, Joint Pain

Headache or joint pain is also one of the symptoms of liver detoxification. This happens due to changes in liver function. If you discover these symptoms are worsening, contact a medical professional immediately for timely treatment.

How to Take Milk Thistle for Liver Detox?

Milk Thistle comes in many different forms, making it convenient for people to use daily. The most popular forms of Milk Thistle are supplements and teas, each with its preparation method, dosage, and benefits.

Supplements

Milk thistle extracts in supplement form are commonly found in capsules, tablets, and liquid extracts. These supplements are standardized to contain a specific amount of Silymarin. Specific dosage ranges from 400 to 600 mg daily, divided into 2 to 3 doses.

Milk Thistle Tea

Soak a spoonful of milk thistle roots, stems, or leaves in hot water for 10-15 minutes. Strain and enjoy up to 3 cups a day to help support overall liver health.

Combine with Other Substances/Herbs

Milk thistle can be combined with other substances or herbs to enhance the liver effectively:

TUDCA (Taurorsodeoxycholic Acid): This acid supports liver health by reducing stress on the liver. Combining milk thistle with TUDCA helps enhance liver protection.

Dandelion: Known for its diuretic properties, dandelion can aid in liver detoxification by increasing urine output and aiding in the removal of toxins from the liver.

Turmeric: With its potent antioxidant properties, turmeric can complement the effects of milk thistle in supporting liver health.

How Much Milk Thistle to Detox the Liver?

What dosage should milk thistle be used to support liver detoxification? Milk thistle is considered safe for the vast majority of patients, even for pregnant or breastfeeding women. The safe amount to use milk thistle extracts is from 400 to 600 mg per day.

Important note: It is best to consult a medical professional before taking any supplement, including milk thistle. Especially if you have an underlying health condition or are taking other medications.

Conclusion

The above article answers the question: Does milk thistle detoxify the liver? Although milk thistle cannot detoxify the liver. Its anti-inflammatory and antioxidant properties can support the liver's natural detoxification process. Above all, a great way to detoxify the liver is to have a healthy lifestyle and a balanced diet. If you are considering taking milk thistle, consult a specialist to determine the appropriate dosage and ensure it does not cause a reaction with any other medications.