Is Lumbrokinase A Blood Thinner?
Lumbrokinase has been studied and used as an enzyme that can thin the blood by reducing blood viscosity and the activity of blood clotting factors. However, it cannot replace prescription blood thinners. Suppose you seek a natural solution to support your health, particularly reducing blood clots. In that case, Lumbrokinase is an up-and-coming option. Let's explore the benefits of Lumbrokinase and answer the question: "Is Lumbrokinase a blood thinner?" through this article.
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Key Takeaways
- Lumbrokinase can thin the blood and reduce the formation of blood clots.
- Lumbrokinase can be applied to cardiovascular health care.
- Lumbrokinase and prescription blood thinners differ in mechanism, side effects, advantages, and disadvantages.
Is Lumbrokinase a Blood Thinner?
Lumbrokinase has blood-thinning effects but cannot replace prescription blood thinners. It has been widely researched and used to support cardiovascular diseases and effectively dissolve blood clots without significant side effects [1].
Lumbrokinase Overview
Benefits of Lumbrokinase
Lumbrokinase is a group of fibrinolytic enzymes extracted from earthworms. Since ancient times, it has been used as a medicinal herb to thin the blood in traditional Chinese medicine. Today, it is increasingly analyzed and researched for its potential to decrease blood clots and reduce and support various cardiovascular diseases.
Supports cardiovascular disease treatment: Research has shown that Lumbrokinase can degrade artificial fibrin and dissolve blood clots in human experiments, improving body circulation [1]. It has also been studied in stroke prevention, where combining Lumbrokinase with Aspirin reduced the recurrence of ischemic strokes [2].
Supports treatment of cerebrovascular diseases: Lumbrokinase significantly reduces fibrinogen levels and serum viscosity, making it an effective supplementary therapy for local cerebral ischemia [3].
Deep vein thrombosis (DVT) and Pulmonary embolism (PE): DVT is a condition where blood clots form in deep veins (usually the leg or thigh). At the same time, PE is a sudden blockage in a lung artery. Studies suggest that combining Lumbrokinase with Warfarin can improve thrombus resolution, accelerating recovery compared to Warfarin alone [4].
Discover details: Lumbrokinase Benefits: Dosage and Side Effects
Mechanism of Lumbrokinase
Lumbrokinase contains plasminogen-activating substances and specific serine proteases for fibrin. Its mechanism of action can be summarized as follows [5]:
- It can activate plasminogen (the inactive form) into plasmin (a clot-dissolving enzyme).
- It directly affects fibrin (the main component of blood clots) to break them down. Importantly, it only works in the presence of fibrin, making it a safer option than other thrombolytic agents.
- Using Lumbrokinase has minimal impact on other proteins in the blood.
Lumbrokinase also exhibits significant advantages in clot-dissolving activity. Its fibrinolytic activity is potent, stable under various environmental conditions, and tolerates organic solvents well [5].
Read more: Can You Take Serrapeptase And Lumbrokinase Together?
Exploring the Benefits of Lumbrokinase for Cardiovascular Health
Based on the studies above, we can summarize the cardiovascular benefits of Lumbrokinase as follows:
Supports coronary artery disease treatment: Oral Lumbrokinase improves body circulation to the heart in myocardial regions, demonstrating potential in supporting coronary artery disease treatment [6].
Supports peripheral artery disease treatment: Lumbrokinase can help improve blood circulation to limbs, increasing the ankle-brachial index (ABI). This helps alleviate symptoms of PAD, such as pain, cramping, and numbness [7].
Deep vein thrombosis (DVT) and Pulmonary embolism (PE): Help support treatment by dissolving blood clots [4].
Blood pressure regulation: Animal studies have shown Lumbrokinase's potential in regulating blood pressure [8]. However, further human studies are needed to ensure safety.
Additionally, Lumbrokinase is used in holistic treatments, particularly at the Oasis Health Institute in Tijuana, Mexico. It has been integrated into comprehensive treatment methods to improve cardiovascular health and reduce the risk of blood clots.
However, caution is advised when using Lumbrokinase as it may increase the risk of bleeding, mainly when used with other blood thinners.
Moreover, initial use may cause symptoms such as stomach pain, diarrhea, abdominal pain, nausea, etc. These symptoms typically subside as the body adjusts to Lumbrokinase. However, if symptoms persist or worsen, immediate medical attention is necessary.
Lumbrokinase Vs. Traditional Blood Thinners
Firstly, it's important to note that Lumbrokinase is not a medication; it is often used as a supplementary method to enhance the body's ability to combat diseases. Lumbrokinase cannot replace prescription blood thinners.
| Features | Lumbrokinase | Traditional Blood Thinners |
| Mechanism | Acts directly on fibrin and fibrinogen to dissolve blood clots, helping to thin the blood | Acts on the blood clotting system by inhibiting clotting factors or platelet aggregation |
| Half-life | Shorter, does not accumulate in the body | Longer |
| Administration | As a dietary supplement | Oral or injectable |
| Advantages | Safe, with fewer side effects | High effectiveness, supported by many studies |
| Disadvantages | Needs more research on effectiveness and safety | Requires regular monitoring, may interact with medications, and more prone to side effects |
When Should You Choose Lumbrokinase or Blood Thinner?
The choice between Lumbrokinase and traditional blood thinners depends on the patient's health condition, specific diseases, and treatment goals. Here are some considerations:
Choose Lumbrokinase if you seek a natural, safe option with fewer side effects. Some patients unable to use traditional blood thinners due to conditions like bleeding tendencies or allergic reactions may also opt for Lumbrokinase.
Choose traditional blood thinners if you have chronic conditions that necessitate long-term treatment or a high risk of recurrent blood clots. Moreover, these medications are advised to lower the risk and manage conditions like coronary artery disease and other clotting disorders.
Understanding your health condition is crucial before deciding between Lumbrokinase and traditional blood thinners. Consulting a doctor is the best approach to determine the most suitable treatment.
Furthermore, you can reduce the risk of blood clot formation with some natural remedies such as:
- Maintaining a healthy diet
- Regular exercise and maintaining a healthy weight
- Avoiding smoking
- Limiting alcohol consumption
- Managing stress effectively
Frequently Asked Questions
Can Lumbrokinase Cause Bleeding?
Lumbrokinase is assessed to have a lower risk of causing bleeding compared to traditional blood thinners. However, it can interact with other medications, potentially increasing the risk of bleeding.
Is Lumbrokinase an Anticoagulant?
Lumbrokinase exhibits the characteristics of a blood thinner [9]. However, it is not an officially recognized blood thinner.
What is the Most Effective Natural Blood Thinner?
Some natural options like Omega-3, ginger, garlic, and turmeric may help thin the blood. However, there is no single most effective natural blood thinner, and these natural options cannot replace prescribed blood thinners. If you are considering any natural blood thinner, consult your doctor to ensure they are safe and suitable.
Conclusion
Lumbrokinase possesses the characteristics of a blood thinner and may help in blood thinning; however, it cannot replace prescribed blood thinners. Lumbrokinase is often considered in cases requiring specific blood thinning effects without severe side effects like other blood thinners. However, for long-term use, professional advice from your doctor is essential.
Related article: Top 5 Best Lumbrokinase Supplements For Cardiovascular Health
References
- [1] Dickey A, Wang N, Cooper E, et al. Transient Expression of Lumbrokinase (PI239) in Tobacco(Nicotiana tabacum)Using a Geminivirus-Based Single Replicon System Dissolves Fibrin and Blood Clots. Evidence-based complementary and alternative medicine. 2017;2017:1-9. doi:https://doi.org/10.1155/2017/6093017
- [2] Sukmawan YP. Lumbrokinase Reduced the Fibrinogen Concentration in Ischemic Cerebrovascular Disease Patients: A Systematic Review and Meta-Analysis. Jurnal Farmasi Klinik Indonesia. 2020;9(1):43-43. doi:https://doi.org/10.15416/ijcp.2020.9.1.43
- [3] Chen Y, Liu Y, Zhang J, et al. Efficacy and safety of lumbrokinase plus aspirin versus aspirin alone for acute ischemic stroke (LUCENT): study protocol for a multicenter randomized controlled trial. Trials. 2022;23(1). doi:https://doi.org/10.1186/s13063-022-06200-4
- [4] Anggia Endah Satuti, H. Hariawan, H. Mumpuni. Effi cacy of Lumbrokinase and Warfarin Compared to Single Warfarin on Thrombus Resolution in Deep Vein Thrombosis. Published 2015. Accessed July 9, 2024. https://www.semanticscholar.org/paper/Effi-cacy-of-Lumbrokinase-and-Warfarin-Compared-to-Satuti-Hariawan/c83eea5cc44402ca90c5e3b62245431058bfcb3c
- [5] Mahendra Kumar Verma, K.K. Pulicherla. Lumbrokinase – A Potent and Stable Fibrin–Specific Plasminogen Activator. ResearchGate. Published June 2011. Accessed July 9, 2024. https://www.researchgate.net/publication/236264109_Lumbrokinase_-_A_Potent_and_Stable_Fibrin-Specific_Plasminogen_Activator
- [6] Improved Myocardial Perfusion in Stable Angina Pectoris by Oral Lumbrokinase: A Pilot Study | The Journal of Alternative and Complementary Medicine. The Journal of Alternative and Complementary Medicine. Published 2021. Accessed July 9, 2024. https://www.liebertpub.com/doi/abs/10.1089/acm.2008.0506
- [7] Agoncillo A. Meta-analysis on the safety and efficacy of Lumbrokinase in peripheral arterial disease. European heart journal Acute cardiovascular care. 2021;10(Supplement_1). doi:https://doi.org/10.1093/ehjacc/zuab020.219
- [8] Sharfina Sharfina, Suryono Suryono, Arief Suseno. Efek Angiogenesis Lumbrokinase terhadap Gambaran Histopatologi Jantung Tikus Galur Wistar Hipertensi Angiogenesis Effect of Lumbrokinase on the Cardiac Histopathology of Hypertensive Wistar Rat. Pustaka Kesehatan. 2015;3(1):24-28. Accessed July 9, 2024. https://jurnal.unej.ac.id/index.php/JPK/article/view/2389
- [9] Metkar SK, Agnishwar Girigoswami, Murugesan R, Koyeli Girigoswami. Lumbrokinase for degradation and reduction of amyloid fibrils associated with amyloidosis. Journal of Applied Biomedicine. 2017;15(2):96-104. doi:https://doi.org/10.1016/j.jab.2017.01.003
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